Digital Biopharmaceutical Manufacturing: Applications in Downstream Debottlenecking and Upstream Process Optimization

Tridiagonal Solutions > Events > Biopharmaceutical, Digital Biopharma, Digital Transformation, Digital Twin, Downstream Debottlenecking > Digital Biopharmaceutical Manufacturing: Applications in Downstream Debottlenecking and Upstream Process Optimization

  • Digital Biopharmaceutical Manufacturing: Applications in Downstream Debottlenecking and Upstream Process Optimization

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  • 25/10/2023 - 10:00 am - 11:00 am EDT
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  • Industry Target: Lifescience

    Digital Transformation has found a vital role in the drug discovery and manufacturing in last few years. Many researchers and operations experts are already leveraging technologies such as data analytics, AI-ML, Generative-AI and Digital Twin in large and medium biopharma and pharma companies. While digitalization in Lifesciences’ upstream operations have already paved a strong foundation by providing more visibility in cells health and growth parameters in bioreactors, downstream processes such as separation and purification are also mining benefits of digitalization.

    During this webinar, we are going to share how advanced analytics techniques are facilitating more process visibility and control in product recovery, capture, virus inactivation, polishing and formulation stages. Hybrid modeling, soft sensors, random Forest, Isolation Forest, FFT and many such digital methods and algorithms are proving their applications in Biopharma. In this session, we are going to share how we could leverage such techniques for the optimization of drug manufacturing.

    Join us for this insightful session if you are a digitalization enthusiast and are responsible for upstream and downstream manufacturing operations, operational excellence, digital transformation, manufacturing analytics and process data analytics.

    Following are some of the interesting topics we will be covering during this webinar:

    Digitalization benefits for Downstream Debottlenecking in bioprocessing:

    • Chromatography and Transition Analysis
    • Crystallization Investigation
    • Membrane Filter Maintenance
    • Predictive Maintenance of PWG
    • Predictive Maintenance of VHP Isolators
    • Predictive Maintenance of Centrifuge

    Process Visibility and Optimization in Upstream process:

    • Application of Hybrid Modeling for Yield Optimization in Bioreactors
    • Batch cycle time analysis and optimization
    • Cell Growth Modeling
    • Seed Bioreactor Optimization

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    Digital Biopharmaceutical Manufacturing: Applications in Downstream Debottlenecking and Upstream Process Optimization

    25/10/202310:00am EDT1 hour

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Pravin, one of the five members of Board of Directors in Tridiagonal Solutions has proven his expertise in creating, positioning and managing high growth companies. Mr. Jain has completed his Bachelors in Computer Engineering from University of Mumbai and Masters in Computer System Engineering from Northeastern University, Boston. He has also completed the Executive Program for Growing Companies at Stanford University Graduate School of Business. He has over 17 years of experience in Technology Entrepreneurship, Business Development and Delivery of Customer Centric Solutions. Pravin’s experience includes acquiring as well as divesting companies. Pravin lived and worked for 14 years in the US, and shifted back to India in the summer of 2006. He has driven, and been accountable for Sales, Marketing, Technology, Delivery and Strategy functions at his previous ventures. Pravin’s previous company grew by over 40x in 6 years and was subsequently divested to Wipro.

Ashish heads the software development activities at Tridiagonal Solutions. He has Post graduate degree in Fluid Mechanics and Thermal Sciences from IIT, Kanpur. Ashish is also a founder member of Tridiagonal and his interests include Computational Fluid Dynamics, Turbulence Modeling, Technical Training and Mentoring along with Open Source Software Development. Before founding Tridiagonal, Ashish worked with Fluent for seven years where he looked after product management responsibilities for Catia and FlowLab products.

Dr. Damodaran Vedapuri heads the North American Operations of Tridiagonal Solutions. He obtained his doctorate from Ohio University. Dr. Vedapuri has wide experience in Computational Fluid Dynamics, Flow Accelerated Corrosion and solving Multiphase Flow Problems of interest to the oil and gas industry. Before joining Tridiagonal, he was employed with SwRI, a premier research lab in the US and at Fluent Inc.

Dr. Damodaran Vedapuri heads the North American Operations of Tridiagonal Solutions. He obtained his doctorate from Ohio University. Dr. Vedapuri has wide experience in Computational Fluid Dynamics, Flow Accelerated Corrosion and solving Multiphase Flow Problems of interest to the oil and gas industry. Before joining Tridiagonal, he was employed with SwRI, a premier research lab in the US and at Fluent Inc.

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