Tridiagonal Solutions > Events > Process Decision Support Using Fundamental Understanding : Upstream Bioprocess Applications
  • Process Decision Support Using Fundamental Understanding : Upstream Bioprocess Applications

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  • 05/05/2022 - 11:00 am - 12:00 pm CDT
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  • Bioreactors are a critical upstream processing operation in the production of a wide range of biopharmaceuticals (MAbs to C&G Therapy products). Operating bioreactors in a robust and reliable manner eases pressure on downstream processing steps, thus increasing overall process reliability and product quality assurance. The only meaningful path to ensure reliable bioreactor operation is via a thorough and pragmatic fundamental understanding of the reactor’s capabilities.

    In this webinar, we will discuss

    a) What fundamental process understanding means and why “process metrics” are the best way to represent process understanding.

    b) How to determine process metrics for various bioreactor systems In addition, attendees will learn how to use process metrics to support the following activities: – scale-up – smart design of experiments – process data analysis (including historical process data and experimental data) – scale-down analysis – operations support

    We will also illustrate these easy-to-implement methodologies using COTS single-use bioreactors from major vendors (Sartorius, Millipore, Pall etc. to name a few).

    We will further show how the information from characterization studies can be used to support process development and technology transfer activities.

     
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Pravin, one of the five members of Board of Directors in Tridiagonal Solutions has proven his expertise in creating, positioning and managing high growth companies. Mr. Jain has completed his Bachelors in Computer Engineering from University of Mumbai and Masters in Computer System Engineering from Northeastern University, Boston. He has also completed the Executive Program for Growing Companies at Stanford University Graduate School of Business. He has over 17 years of experience in Technology Entrepreneurship, Business Development and Delivery of Customer Centric Solutions. Pravin’s experience includes acquiring as well as divesting companies. Pravin lived and worked for 14 years in the US, and shifted back to India in the summer of 2006. He has driven, and been accountable for Sales, Marketing, Technology, Delivery and Strategy functions at his previous ventures. Pravin’s previous company grew by over 40x in 6 years and was subsequently divested to Wipro.

Ashish heads the software development activities at Tridiagonal Solutions. He has Post graduate degree in Fluid Mechanics and Thermal Sciences from IIT, Kanpur. Ashish is also a founder member of Tridiagonal and his interests include Computational Fluid Dynamics, Turbulence Modeling, Technical Training and Mentoring along with Open Source Software Development. Before founding Tridiagonal, Ashish worked with Fluent for seven years where he looked after product management responsibilities for Catia and FlowLab products.

Dr. Damodaran Vedapuri heads the North American Operations of Tridiagonal Solutions. He obtained his doctorate from Ohio University. Dr. Vedapuri has wide experience in Computational Fluid Dynamics, Flow Accelerated Corrosion and solving Multiphase Flow Problems of interest to the oil and gas industry. Before joining Tridiagonal, he was employed with SwRI, a premier research lab in the US and at Fluent Inc.

Dr. Damodaran Vedapuri heads the North American Operations of Tridiagonal Solutions. He obtained his doctorate from Ohio University. Dr. Vedapuri has wide experience in Computational Fluid Dynamics, Flow Accelerated Corrosion and solving Multiphase Flow Problems of interest to the oil and gas industry. Before joining Tridiagonal, he was employed with SwRI, a premier research lab in the US and at Fluent Inc.

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